A glucocorticoid not normally secreted in significant quantities by the human adrenal cortex. Endogenously, it is probably a metabolite of hydrocortisone but exhibits no biological activity until converted to hydrocortisone (cortisol); it acts upon carbohydrate metabolism and influences the nutrition and growth of connective (collagenous) tissues. It was the first glucocorticoid available for therapy. SYN: Wintersteiner compound F.

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cor·ti·sone -.sōn, -.zōn n a glucocorticoid C21H28O5 that is produced naturally in small amounts by the adrenal cortex and is administered in the form of its synthetic acetate C23H30O6 esp. as replacement therapy for deficient adrenocortical secretion and as an anti-inflammatory agent (as for rheumatoid arthritis) compare 11-dehydrocorticosterone

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a naturally occurring corticosteroid that is used mainly to treat deficiency of corticosteroid hormones in Addison's disease and following surgical removal of the adrenal glands. It is administered by mouth or injection and may cause serious side-effects such as stomach ulcers and bleeding, nervous and hormone disturbances, muscle and bone damage, and eye changes.

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cor·ti·sone (korґtĭ-sōn) a natural glucocorticoid that is metabolically convertible to cortisol. The human adrenal cortex secretes only minute amounts; most that is found in peripheral plasma is formed from cortisol by a reversible reaction. The synthetic hormone exerts its pharmaceutical effects through its metabolic conversion to cortisol.

Medical dictionary. 2011.

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  • cortisone — [ kɔrtizɔn ] n. f. • 1950; mot angl. , de corti(co) s(ter)one ♦ Hormone du cortex surrénal, employée en thérapeutique. ● cortisone nom féminin (américain cortisone, de cortico sterone) Hormone de la famille des glucocorticostéroïdes, sécrétée par …   Encyclopédie Universelle

  • Cortisone — Général Nom IUPAC 17,21 dihydroxypregn 4 ene 3 …   Wikipédia en Français

  • cortisone — n. (Chem.) a corticosteroid hormone ({C21H28O5}) produced by the adrenal cortex. It is used in medicine as an antiinflammatory agent. [WordNet 1.5] …   The Collaborative International Dictionary of English

  • cortisone — 1949, coined by its discoverer, Dr. Edward C. Kendall, shortening of chemical name, 17 hydroxy 11 dehydrocorticosterone, ultimately from L. corticis (gen. of cortex; see CORTEX (Cf. cortex)). So called because it was obtained from the cortex of… …   Etymology dictionary

  • cortisone — ► NOUN ▪ a steroid hormone produced by the adrenal cortex and used as an anti inflammatory and anti allergy agent. ORIGIN from elements of its chemical name …   English terms dictionary

  • cortisone — ☆ cortisone [kôrt′ə sōn΄, kôrt′əzōn΄ ] n. [contr. < CORTICOSTERONE: so named by Edward C. Kendall (1886 1972), U.S. physician] a corticosteroid, C21H28O5, used as a replacement in adrenal insufficiency and in the treatment of various… …   English World dictionary

  • Cortisone — Not to be confused with cortisol (a.k.a. hydrocortisone), a similar compound with a similar name, genesis, and function. Cortisone …   Wikipedia

  • cortisone — /kawr teuh zohn , sohn /, n. 1. Biochem. a steroid hormone of the adrenal cortex, C21H28O5, active in carbohydrate and protein metabolism. 2. Pharm. a commercial form of this compound, obtained by extraction from the adrenal glands of certain… …   Universalium

  • cortisone — cor·ti·só·ne s.m. TS biochim., farm. sostanza ormonale estraibile dalla ghiandola surrenale od ottenibile per sintesi, attiva sui processi infiammatori e depressiva dei meccanismi immunitari e autoimmunitari, efficace nella cura dell asma, di… …   Dizionario italiano

  • cortisone — cor|ti|sone [ˈko:tızəun US ˈko:rtısoun] n [U] [Date: 1900 2000; Origin: corticosterone type of hormone (20 21 centuries), from cortex + sterol ( STEROID) + one; because it is produced by the outer layer of a body organ] a ↑hormone that is used… …   Dictionary of contemporary English

  • cortisone — [[t]kɔ͟ː(r)tɪzoʊn[/t]] N UNCOUNT Cortisone is a hormone used in the treatment of arthritis, allergies, and some skin diseases …   English dictionary

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