genetic disease, human — Introduction any of the diseases and disorders that are caused by mutations in one or more genes (gene). With the increasing ability to control infectious and nutritional diseases in developed countries, there has come the realization … Universalium
Propositus — A male through whom a family medically comes to light (is first ascertained). Also called the proband or index case. The feminine of propositus is proposita. * * * 1. Proband, usually referring to the first index case to be ascertained.… … Medical dictionary
ancestor — A person in the direct line of descent from which a subject of interest is derived (parents, grandparents, etc.; but no collaterals or descendants). leading a. in genetic counseling given to a consultand unaffected by but possibly a carrier or a… … Medical dictionary
encu — Acronym for equivalent normal child unit, that amount of information from any source (linkage analysis, parental, and collateral phenotypes, biochemistry of the carrier state, etc.) that will have the same impact on the probability as one usual… … Medical dictionary
ensu — Acronym for equivalent normal son unit, that amount of information from any source (linkage, carrier, phenotype, etc.) that will have the same impact on the conditional probability that a female consultand is a carrier for an X linked trait as… … Medical dictionary