Colony-stimulating factor

Colony-stimulating factor
A laboratory-made agent similar to a substance in the body that stimulates the production of blood cells. Treatment with colony-stimulating factors (CSFs) can help the blood- forming tissue recover from the effects of chemotherapy and radiation therapy. The CSFs include granulocyte colony-stimulating factors (G-CSF) and granulocyte-macrophage colony-stimulating factors (GM-CSF).

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col·o·ny-stim·u·lat·ing factor -.stim-yə-.lāt-iŋ- n any of several glycoproteins that promote the differentiation of stem cells esp. into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture see GRANULOCYTE COLONY-STIMULATING FACTOR, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR, INTERLEUKIN-3, MACROPHAGE COLONY-STIMULATING FACTOR

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one of a group of substances (haemopoietic growth factors or hormones) that are produced in the bone marrow and stimulate the production of specific blood cells. Genetically engineered granulocyte colony-stimulating factor (G-CSF) stimulates neutrophil production and also limits bone marrow toxicity from chemotherapy.

Medical dictionary. 2011.

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