vaccinia virus

vaccinia virus
a virus of the genus Orthopoxvirus that does not occur in nature, being propagated only in the laboratory. It is used to prepare vaccine against smallpox and is also used as in research as a vector for antigens of other microorganisms. The present virus is derived from the original one used by Jenner, obtained from the lesions of cowpox, but the origin of the original virus remains unclear. Some believe that vaccinia virus is a derivative of the immunologically similar but antigenically different viruses of cowpox and variola (smallpox), while others think that it may be a recombinant of these viruses.

Medical dictionary. 2011.

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