cofactor

cofactor
1. SYN: coenzyme. 2. An atom or molecule essential for the action of a large molecule; e.g., heme in hemoglobin, magnesium in chlorophyll. Solo metal ions are regarded as cofactors for proteins, but not as coenzymes.
- cobra venom c. equivalent in action to C3B, which means that it can activate the alternative complement pathway.
- molybdenum c. (mo-lib′de-num) a complex of molybdenum and molybdopterin required for a number of enzymes. A deficiency of this c. will result in lower activities of sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase causing elevated levels of sulfite, thiosulfite, xanthine, etc.
- platelet c. I SYN: factor VIII.
- platelet c. II SYN: factor IX.

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co·fac·tor 'kō-.fak-tər n
1) a substance that acts with another substance to bring about certain effects esp COENZYME
2) something (as a diet or virus) that acts with or aids another factor in causing disease

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n.
a nonprotein substance that must be present in suitable amounts before certain enzyme can act. Cofactors include coenzyme and metal ions (e.g. sodium and potassium ions).

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co·fac·tor (koґfak-tər) an element or principle, as a coenzyme, with which another must unite in order to function.

Medical dictionary. 2011.

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  • Cofactor — may refer to any of the following: Cofactor (linear algebra), the signed minor of a matrix Minor (linear algebra), an alternative name for the determinant of a smaller matrix than that which it describes Cofactor (biochemistry), a substance that… …   Wikipedia

  • Cofactor — cofactor. m. Factor que, en unión de otros, contribuye a producir algo. * * * Un cofactor es una molécula orgánica o inorgánica, termoestable y de bajo peso molecular, necesaria para la acción de una enzima. * * * Un átomo, molécula orgánica, o… …   Enciclopedia Universal

  • cofactor — m. Factor que, en unión de otros, contribuye a producir algo …   Diccionario de la lengua española

  • cofactor — [kō′fak΄tər] n. 1. any one of two or more factors, the combined effects of which may cause a certain result or condition, esp. a disease: also written co factor 2. Biochem. an accessory substance, esp. a coenzyme, that must be present for a… …   English World dictionary

  • cofactor — /koh fak teuhr/, n. 1. Biochem. any of various organic or inorganic substances necessary to the function of an enzyme. 2. Math. a. a prefactor or postfactor. b. the product of the minor of a given element of a matrix times 1 raised to the power… …   Universalium

  • Cofactor — Un cofactor es un componente no proteico, termoestable y de bajo peso molecular, necesario para la acción de una enzima. El cofactor se une a una estructura proteica denominada apoenzima, y a este complejo se le denomina holoenzima. Entre los… …   Wikipedia Español

  • cofactor — {{#}}{{LM C09147}}{{〓}} {{[}}cofactor{{]}} ‹co·fac·tor› {{《}}▍ s.m.{{》}} Elemento que puede contribuir a producir algo: • Esta enfermedad es difícil de prevenir porque pueden darse muchos cofactores que contribuyan a su aparición.{{○}} …   Diccionario de uso del español actual con sinónimos y antónimos

  • cofactor — kofaktorius statusas T sritis chemija apibrėžtis Mažos molekulinės masės organinis arba neorganinis junginys, lemiantis fermento aktyvumą. atitikmenys: angl. cofactor rus. кофактор …   Chemijos terminų aiškinamasis žodynas

  • Cofactor Engineering — Cofactor engineering, a subset of metabolic engineering, is defined as the manipulation of the use of cofactors in an organism’s metabolic pathways. The field has applications in industry, chemical manufacturing, and pharmaceuticals.[1] Cofactors …   Wikipedia

  • Cofactor Genomics — Type Private Industry Biotechnology and Bioinformatics Services Founded St. Louis, Missouri, U.S. (2008 (2008)) Headquarters …   Wikipedia

  • Cofactor of BRCA1 — Identifiers Symbols COBRA1; DKFZp586B0519; KIAA1182; NELF B; NELFB External IDs …   Wikipedia

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