uroporphyrinogen-III synthase

uroporphyrinogen-III synthase
uro·por·phy·rin·o·gen-III syn·thase (u″ro-por″fə-rinґə-jən sinґthās) [EC 4.2.1.75] an enzyme of the lyase class that acts concertedly with hydroxymethylbilane synthase to convert porphobilinogen to uroporphyrinogen III in the biosynthesis of porphyrins and heme. Deficiency of the enzyme, an autosomal recessive trait, causes congenital erythropoietic porphyria. Called also uroporphyrinogen III cosynthase.

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  • Uroporphyrinogen III synthase — protein Name = uroporphyrinogen III synthase caption = width = HGNCid = 12592 Symbol = UROS AltSymbols = EntrezGene = 7390 OMIM = 606938 RefSeq = NM 000375 UniProt = P10746 PDB = ECnumber = 4.2.1.75 Chromosome = 10 Arm = q Band = 25.2 26.3… …   Wikipedia

  • Uroporphyrinogen III — Chembox new ImageFile=Uroporphyrinogen III skeletal.svg ImageSize= IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=1976 85 8 PubChem=1179 SMILES= MeSHName=Uroporphyrinogen+III Section2= Chembox Properties Formula=C40H44N4O16… …   Wikipedia

  • uroporphyrinogen III cosynthase — uro·por·phy·rin·o·gen III co·syn·thase (u″ro por″fə rinґə jən ko sinґthās) uroporphyrinogen III synthase …   Medical dictionary

  • Uroporphyrinogen — Uroporphyrinogens are tetrapyrroles with four propionic acid groups and four acetic acid groups.There are four forms, which vary based upon the arrangements of the groups ( P ) and ( A ): * In the I variety, clockwise, the order repeats four… …   Wikipedia

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  • hydroxymethylbilane synthase — hy·droxy·meth·yl·bil·ane syn·thase (hi drok″se meth″əl bilґān sinґthās) [EC 2.5.1.61] an enzyme of the transferase class that catalyzes the deamination and condensation of four molecules of porphobilinogen to form a… …   Medical dictionary

  • Metabolism — Cell metabolism redirects here. For the journal, see Cell Metabolism. Structure of adenosine triphosphate, a central intermediate in energy metabolism Metabolism (from Greek: μεταβολή metabolē , change or Greek: μεταβολισμός metabolismos,… …   Wikipedia

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