uroporphyrinogen decarboxylase

uroporphyrinogen decarboxylase
uro·por·phy·rin·o·gen de·car·boxy·lase (u″ro-por″fə-rinґə-jən de-kahr-bokґsə-lās) [EC 4.1.1.37] an enzyme of the lyase class that catalyzes the decarboxylation of uroporphyrinogen III to coproporphyrinogen III in the biosynthesis of heme. Decreased enzyme activity is associated with porphyria cutanea tarda and the variant hepatoerythropoietic porphyria.

Medical dictionary. 2011.

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