UDP-glucose 4-epimerase

UDP-glucose 4-epimerase
UDP-glu·cose 4-epim·er·ase (glooґkōs ə-pimґər-ās) [EC 5.1.3.2] an enzyme of the isomerase class that catalyzes the interconversion of UDP-galactose and UDP-glucose in the metabolism of galactose, requiring NAD+ as a cofactor. Deficiency of the enzyme in erythrocytes, an autosomal recessive trait, causes accumulation in red cells of galactose 1-phosphate. Called also UDP-galactose 4-epimerase.

Medical dictionary. 2011.

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  • UDP-glucose 4-epimerase — In enzymology, an UDP glucose 4 epimerase (EC number|5.1.3.2) is an enzyme that catalyzes the chemical reaction:UDP glucose ightleftharpoons UDP galactoseHence, this enzyme has one substrate, UDP glucose, and one product, UDP galactose.This… …   Wikipedia

  • UDP-glucose 4-epimerase deficiency — UDP glu·cose 4 epim·er·ase de·fi·cien·cy (glooґkōs ə pimґər ās) a form of galactosemia caused by mutations in the GALE gene (locus: 1p36 p35), which encodes UDP glucose 4 epimerase. There are two forms: one is benign and… …   Medical dictionary

  • UDP-galactose 4-epimerase — UDP ga·lac·tose 4 epim·er·ase (gə lakґtōs ə pimґər ās) UDP glucose 4 epimerase …   Medical dictionary

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