- 1. To coagulate, said especially of blood. 2. A soft, nonrigid, insoluble mass formed when a liquid ( e.g., blood or lymph) gels. [O.E. klott, lump]- antemortem c. a blood c., found at autopsy, formed in any of the heart cavities or the great vessels before death.- blood c. the coagulated phase of blood; the soft, coherent, jelly-like red mass resulting from the conversion of fibrinogen to fibrin, thereby entrapping the red blood cells (and other formed elements) within the coagulated plasma.- currant jelly c. a jellylike mass of red blood cells and fibrin formed by the in vitro or postmortem clotting of whole or sedimented blood.- laminated c. a c. formed in a succession of layers such as occurs in the natural course of an aneurysm.- passive c. a c. formed in an aneurysmal sac consequent to the cessation or slowing of circulation through the aneurysm.* * *Clinical Perspectives on Lysis of Thrombi [study]
* * *clot 'klät n a coagulated mass produced by clotting of bloodclot vb, clot·ted; clot·ting vi to undergo a sequence of complex chemical and physical reactions that results in conversion of fluid blood into a coagulum and that involves shedding of blood, release of thromboplastin from blood platelets and injured tissues, inactivation of heparin by thromboplastin permitting calcium ions of the plasma to convert prothrombin to thrombin, interaction of thrombin with fibrinogen to form an insoluble fibrin network in which blood cells and plasma are trapped, and contraction of the network to squeeze out excess fluid: COAGULATE vt to cause to form into or as if into a clot
* * *(klot) 1. a semisolidified mass, as of blood or lymph; called also coagulum. 2. blood c. coagulate.
Medical dictionary. 2011.