Cogan syndrome

Cogan syndrome
Arteritis (also referred to as vasculitis) that involves the ear. This condition is called Cogan syndrome after the American ophthalmologist David Glendenning Cogan (1908-93) who first described it. Cogan syndrome features not only problems of the hearing and balance portions of the ear, but also inflammation of the front of the eye (the cornea) and often fever, fatigue, and weight loss. Joint and muscle pains can also be present. Less frequently, the arteritis can involve blood vessels elsewhere in the body as in the skin, kidneys, nerves, and other tissues and organs. Cogan syndrome can lead to deafness or blindness. The treatment of Cogan syndrome is directed toward stopping the inflammation of the blood vessels. Cortisone-related medications, such as prednisone, are often used. Some patients with severe disease can require immune suppression medications, such as cyclophosphamide(CYTOXAN). Cogan syndrome is extremely rare and its cause is not known.

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1. nonsyphilitic interstitial keratitis with tinnitus and deafness; it usually occurs in children, often associated with polyarteritis nodosa. 2. Cogan oculomotor apraxia.

Medical dictionary. 2011.

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  • Cogan oculomotor apraxia — congenital oculomotor apraxia an absence or defect of horizontal eye movements, so that when the patient tries to look at an object off to one side, the head must turn to bring the eyes into line with the object and the eyes exhibit nystagmus;… …   Medical dictionary

  • Syndrome de cogan — CIM 10: M30.8 {{{CIM10}}}.0 {{{X.0}}} …   Wikipédia en Français

  • Syndrome de Cogan — CIM 10 : M30.8 Le syndrome de Cogan se définit par l association d une kératite interstitielle à une atteinte audiovestibulaire. Il a été décrit en 1934 (ou 1945[1]). Dans la plupart des cas, s y associent d autres manifestations de… …   Wikipédia en Français

  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

  • Cogan oculomotor apraxia syndrome — Co·gan oc·u·lo·mo·tor aprax·ia, syndrome (koґgən) [David Glendenning Cogan, American ophthalmologist, 1908–1993] see under apraxia and syndrome …   Medical dictionary

  • Cogan's syndrome — a disorder in which keratitis and iridocyclitis (see uveitis) are associated with tinnitus, vertigo, and bilateral sensorineural deafness. D. G. Cogan (1908 93), US ophthalmologist …   Medical dictionary

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