- blast transformation
- lymphocyte transformation the morphologic changes accompanying lymphocyte activation, in which small, resting lymphocytes are transformed into large, active lymphocytes (lymphoblasts).
Medical dictionary. 2011.
blast transformation
Look at other dictionaries:
blast transformation — The morphological and biochemical changes in B and T lymphocytes on exposure to antigen or to a mitogen. The cells appear to move from G0 to G1 stage of the cell cycle. They usually enlarge and proceed to S phase and mitosis later. The process… … Dictionary of molecular biology
transformation — Any alteration in the properties of a cell that is stably inherited by its progeny. Classical example was the transformation of Diplococcus pneumoniae to virulence by DNA, achieved in 1944 by Avery, MacLeod & McCarty. Currently usually refers to… … Dictionary of molecular biology
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lymphocyte transformation — n a transformation caused in lymphocytes by a mitosis inducing agent (as phytohemagglutinin) or by a second exposure to an antigen and characterized by an increase in size and in the amount of cytoplasm, by visibility of nucleoli in the nucleus,… … Medical dictionary
