type I topoisomerase
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Type II topoisomerase — Type II topoisomerases cut both strands of the DNA helix simultaneously in order to change the linking number of the molecule. FunctionOnce cut, the ends of the DNA are separated, and a second DNA duplex is passed through the break. Following… … Wikipedia
Type I topoisomerase — Type I topoisomerases are divided into two structurally and mechanistically distinct topoisomerases: type IA and type IB. * Type IA topoisomerases change the linking number of a circular DNA strand by units of strictly 1. * Type IB topoisomerases … Wikipedia
type II topoisomerase — DNA topoisomerase (ATP hydrolyzing) … Medical dictionary
Topoisomerase inhibitor — Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymescite web |url=http://www.cancer.gov/Templates/db alpha.aspx?CdrID=46665 |title=Definition of topoisomerase inhibitor NCI Dictionary of Cancer Terms… … Wikipedia
Topoisomerase IV — is one of two type II topoisomerases in bacteria, the other being DNA gyrase. Like gyrase, topoisomerase IV is able to pass one double strand of DNA through another double strand of DNA, thereby changing the linking number of DNA by two in each… … Wikipedia
Topoisomerase — Topoisomerases (type I: EC 5.99.1.2, type II: EC 5.99.1.3) are enzymes that regulate the overwinding or underwinding of DNA. The winding problem of DNA arises due to the intertwined nature of its double helical structure. For example, during DNA… … Wikipedia
Topoisomerase II — ADN topoïsomérase Les ADN topoïsomérases (de type I : ADN topo isomérases et de type II : ADN gyrases) sont des enzymes qui contrôlent la structure topologique de l’ADN en générant des coupures transitoires dans celui ci et en… … Wikipédia en Français
Topoisomérase — ADN topoïsomérase Les ADN topoïsomérases (de type I : ADN topo isomérases et de type II : ADN gyrases) sont des enzymes qui contrôlent la structure topologique de l’ADN en générant des coupures transitoires dans celui ci et en… … Wikipédia en Français
Topoisomérase II — ADN topoïsomérase Les ADN topoïsomérases (de type I : ADN topo isomérases et de type II : ADN gyrases) sont des enzymes qui contrôlent la structure topologique de l’ADN en générant des coupures transitoires dans celui ci et en… … Wikipédia en Français
topoisomerase II inhibitor RTA 744 — A substance being studied in the treatment of adult brain tumors. Topoisomerase II inhibitor RTA 744 crosses the blood brain barrier and blocks an enzyme needed for cancer growth. It is a type of topoisomerase inhibitor. Also called RTA 744 … English dictionary of cancer terms
