- - ATP c. (pro-3S)-lyase an enzyme that catalyzes the reaction of ATP, c., and coenzyme A to form ADP, orthophosphate, oxaloacetate, and acetyl-CoA. An important step in fatty acid biosynthesis. SYN: c.-cleavage enzyme.- c. lyase c. (pro-3S)-lyase; an enzyme that catalyzes the cleavage of c. to oxaloacetate and acetate, in the absence of coenzyme A. SYN: citrase, citratase, c. aldolase.- c. synthase c. (si)-synthase; an enzyme catalyzing the condensation of oxaloacetate, water, and acetyl-CoA, forming c. and coenzyme A; an important step in the tricarboxylic acid cycle. SYN: condensing enzyme, oxaloacetate transacetase.
* * *cit·rate 'si-.trāt n a salt or ester of citric acid
* * *cit·rate (sitґrāt) any anionic form, salt, or ester of citric acid. For specific salts, see entries under the adjectival form, e.g., for ferric citrate, see under ferric.
Medical dictionary. 2011.