- A histamine analogue and antagonist used to treat peptic ulcer and hypersecretory conditions by blocking histamine H2 receptor sites, thus inhibiting gastric acid secretion.
* * *ci·met·i·dine sī-'met-ə-.dēn n an H2 antagonist C10H16N6S that like histamine contains the ring structure of imidazole and is used to inhibit gastric acid secretion in conditions in which such secretion produces duodenal or gastric ulcers or erosive lesions (as in serious cases of gastroesophageal reflux disease) see TAGAMET
* * *n.an H2-receptor antagonist (see antihistamine) that is used to treat stomach and duodenal ulcers, gastro-oesophageal reflux disease, and other digestive disorders. It is administered by mouth or injection and the most common side-effects are dizziness, diarrhoea, muscular pains, and rash. Trade names: Dyspamet, Galenamet, Tagamet.
* * *ci·met·i·dine (si-metґĭ-dēn) [USP] a histamine H2 receptor antagonist; it inhibits gastric acid secretion and is used in the prophylaxis and treatment of peptic ulcer, the relief of symptoms associated with hyperacidity, and the treatment of gastroesophageal reflux disease, of upper gastrointestinal bleeding, and of pathologic gastric hypersecretion, as that associated with Zollinger-Ellison syndrome; administered orally.
Medical dictionary. 2011.