chymopapain

chymopapain
A cysteine proteinase similar to papain in specificity; on rare occasions, it is used to shrink slipped disks as an alternative to surgery; used as a meat tenderizer. It is the major endopeptidase of papaya.

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chy·mo·pa·pa·in .kī-mō-pə-'pā-ən, -'pī-ən n a proteolytic enzyme from the latex of the papaya that is used in meat tenderizer and has been used medically in chemonucleolysis

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chy·mo·pa·pain (ki″mo-pə-pānґ) [EC 3.4.22.6] an enzyme of the hydrolase class, a cysteine endopeptidase, that catalyzes the hydrolysis of proteins and polypeptides. Its specificity is very close to that of papain and both occur in the latex of the tropical papaya tree, Carica papaya. The enzyme is used to break down the proteoglycan portion of the nucleus pulposus in the treatment of herniation of intervertebral (lumbar) disks by chemonucleolysis.

Medical dictionary. 2011.

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  • Chymopapain — Clinical data Pregnancy cat.  ? Legal status ℞ Prescription only Routes Injection into intervertebral disc Identifiers …   Wikipedia

  • chymopapain — [kī΄mō pə pā′in, kī΄mō pəpī′in] n. papain, esp. when injected into a slipped disk to dissolve pain causing soft cartilage …   English World dictionary

  • chymopapain — /kuy moh peuh pay in, puy in/, n. Pharm. an enzyme derived from the tropical papaya fruit that is used in some circumstances to treat herniated disks. [1970 75; CHYME + O + PAPAIN] * * * …   Universalium

  • Chymopapain — Chy|mo|pa|pa|in [↑ Chymo u. ↑ Papain], das; s, e: aus Papayamilchsaft gewinnbare Peptidase, die med. zur ↑ Chemonukleolyse eingesetzt wird …   Universal-Lexikon

  • chymopapain — chy·mo·papain …   English syllables

  • chymopapain — chy•mo•pa•pa•in [[t]ˌkaɪ moʊ pəˈpeɪ ɪn, ˈpaɪ ɪn[/t]] n. biochem. an enzyme of the papaya that is capable of breaking down protein: used to dissolve cartilage in the treatment of herniated disks • Etymology: 1970–75 …   From formal English to slang

  • chymopapain — ¦kīmōˌ noun Etymology: chyme + o + papain : a proteolytic enzyme from the latex of the papaya that is used in meat tenderizer and has been used medically in chemonucleolysis * * * /kuy moh peuh pay in, puy in/, n. Pharm. an enzyme derived from… …   Useful english dictionary

  • chemonucleolysis — Injection of chymopapain into the nucleus pulposus of an intervertebral disk. A therapeutic option for the treatment of a herniated nucleus pulposis, e.g., “slipped disk.” * * * che·mo·nu·cle·ol·y·sis .n( …   Medical dictionary

  • Chemonukleolyse — Che|mo|nu|k|le|o|ly|se [↑ chem , nukl (1) u. ↑ lyse], die; , n: die Auflösung des Gallertkerns von Bandscheiben (Nukleolyse) mit chem., eigtl. enzymatischen Mitteln, z. B. Chymopapain oder Kollagenase. * * * Chemonukleolyse,  … …   Universal-Lexikon

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

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