X-linked lymphoproliferative syndrome

X-linked lymphoproliferative syndrome
an X-linked immunodeficiency disorder caused by mutation in either the SHD2D1A or XIAP gene (both at locus Xq25), which are involved in T-cell development and apoptosis; the disorder is characterized by defective cellular or humoral immune response to infection with Epstein-Barr virus. Fulminant infectious mononucleosis, fatal B cell malignancies, or hypogammaglobulinemia can result from viral infection. Called also Duncan s. and Purtilo s.

Medical dictionary. 2011.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • X-linked lymphoproliferative syndrome — (XLP syndrome, Duncan s disease) a hereditary disorder of the immune system caused by a defective sex linked gene carried on an X chromosome. There is uncontrolled proliferation of B lymphocyte in response to infection by the Epstein Barr virus,… …   Medical dictionary

  • X-linked lymphoproliferative syndrome — XLP syndrome; = Duncan s disease a hereditary disorder of the immune system caused by a defective sex linked gene carried on an X chromosome. There is uncontrolled proliferation of B lymphocytes in response to infection by the Epstein Barr virus …   The new mediacal dictionary

  • X-linked lymphoproliferative disease — Classification and external resources ICD 10 D82.3 OMIM 308240 300635 …   Wikipedia

  • X-linked lymphoproliferative disease — see under syndrome …   Medical dictionary

  • Lymphoproliferative disorders — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD9 = ICD9|238.79 ICDO = OMIM = MedlinePlus = eMedicineSubj = ped eMedicineTopic = 1345 MeshID = D008232 Lymphoproliferative disorders (LPDs) refer to several conditions in which… …   Wikipedia

  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

  • Duncan syndrome — Dun·can syndrome (dungґkən) [Duncan, the original kindred in which the disease was described] X linked lymphoproliferative syndrome; see under syndrome …   Medical dictionary

  • Purtilo syndrome — Pur·ti·lo syndrome (pər teґlo) [David T. Purtilo, American physician, 20th century] X linked lymphoproliferative syndrome; see under syndrome …   Medical dictionary

  • XLP syndrome — see X linked lymphoproliferative syndrome …   Medical dictionary

  • XLP syndrome — see X linked lymphoproliferative syndrome …   The new mediacal dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”