sea-blue histiocyte syndrome

sea-blue histiocyte syndrome
a rare disorder characterized by the presence of abnormal histiocytes that stain blue with Wright and Giemsa stains (sea-blue histiocytes), accompanied by splenomegaly. Clinically it may range from a benign course with mild purpura secondary to thrombocytopenia, to progressive cirrhosis, hepatic failure, and death. The etiology is unknown, but sometimes it is inherited as an autosomal recessive condition. Called also sea-blue histiocytosis.

Medical dictionary. 2011.

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