chromatolysis

chromatolysis
The disintegration of the granules of chromophil substance (Nissl bodies) in a nerve cell body that may occur after exhaustion of the cell or damage to its peripheral process; other changes considered part of c. include swelling of the perikaryon and shifting of the nucleus from its central position to the periphery. SYN: chromatinolysis, chromolysis, tigrolysis. [chromato- + G. lysis, dissolution]
- central c. c. associated with significant axonal injury. SYN: retrograde c..
- retrograde c. SYN: central c..
- transsynaptic c. SYN: transsynaptic degeneration.

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chro·ma·tol·y·sis .krō-mə-'täl-ə-səs n, pl -y·ses -.sēz the dissolution and breaking up of chromophil material (as chromatin) of a cell and esp. a neuron
chro·mato·lyt·ic krō-.mat-əl-'it-ik, krə- adj

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n.
the dispersal or disintegration of the microscopic structures within the nerve cells that normally produce proteins. It is part of the cell's response to injury.

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chro·ma·tol·y·sis (kro″mə-tolґə-sis) [chromato- + -lysis] disintegration of the Nissl (chromophil) bodies of a nerve cell as the result of injury, or of fatigue or exhaustion; a part of the axon reaction (q.v.).

Medical dictionary. 2011.

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Look at other dictionaries:

  • Chromatolysis — is the dissolution of the Nissl bodies in the cell body of a neuron. It is an induced response of the cell usually triggered by axotomy (severing or damaging of the axon), ischemia, toxicity to the cell, cell exhaustion, virus infections, and… …   Wikipedia

  • chromatolysis — [krō΄mətäl′ə sis] n. pl. chromatolyses [krō΄mə tual′əsēz΄] [ CHROMATO + LYSIS] Med. the disappearance of certain chromophil granules from nerve cells chromatolytic [krō mat΄ə lit′ik] adj …   English World dictionary

  • chromatolysis — noun Etymology: New Latin Date: 1901 the dissolution and breaking up of chromophil material (as chromatin) of a cell and especially a nerve cell • chromatolytic adjective …   New Collegiate Dictionary

  • chromatolysis — n. [Gr. chroma, color; lysein, to loosen] The solution and breaking up of chromatin; chromatolytic adj …   Dictionary of invertebrate zoology

  • chromatolysis — chromatolytic /kreuh mat l it ik, kroh meuh tl it /, adj. /kroh meuh tol euh sis/, n. Cell Biol., Pathol. the dissolution and disintegration of chromatin. [1900 05; CHROMATO + LYSIS] * * * …   Universalium

  • chromatolysis — n. dissolution and break down of chromatin (Chemistry) …   English contemporary dictionary

  • chromatolysis — chro·ma·tol·y·sis …   English syllables

  • chromatolysis — n. the dispersal or disintegration of the microscopic structures within the nerve cells that normally produce proteins. It is part of the cell s response to injury …   The new mediacal dictionary

  • chromatolysis — /kroʊməˈtɒləsəs/ (say krohmuh toluhsuhs) noun the dissolution and disintegration of chromatin …  

  • chromatolysis — …   Useful english dictionary

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