- Literally a fragment, the word in modern medical science has come to mean a replica, for example, of a group of bacteria or a macromolecule such as DNA. Clone also refers to an individual developed from a single somatic (non-germ) cell from a parent, representing an exact replica of that parent. A clone is a group of cells derived from a single ancestral cell.
* * *1. A colony or group of organisms (or an individual organism), or a colony of cells derived from a single organism or cell by asexual reproduction, all having identical genetic constitutions. 2. To produce such a colony or individual. 3. A short section of DNA that has been copied by means of gene cloning. See cloning. 4. A homogeneous population of DNA molecules. [G. klon, slip, cutting used for propagation]
* * *clone 'klōn n1) the aggregate of the asexually produced progeny of an individual also a group of replicas of all or part of a macromolecule (as DNA or an antibody)2) an individual grown from a single somatic cell of its parent and genetically identical to itclon·al 'klōn-əl adjclon·al·ly -əl-ē advclone vb, cloned; clon·ing vt to propagate a clone from <frogs have been successfully cloned by transplanting nuclei from body cells to enucleated eggs> vi to produce a clone
* * *1. n. a group of cells (usually bacteria) descended from a single cell by asexual reproduction and therefore genetically identical to each other and to the parent cell.2. n. an organism derived from a single cell of its parent and therefore genetically identical to it. The first cloned animal, born in 1997, was produced by fusing a somatic nucleus of the parent with a denucleated egg cell of a second animal. The resulting 'embryo' was implanted into the uterus of a third animal to complete its development.3. n. (gene clone) a group of identical genes produced by genetic engineering. The parent gene is isolated using restriction enzyme and inserted, via a cloning vector (e.g. a bacteriophage), into a bacterium, in which it is replicated. See also vector.4. vb. to form a clone.
* * *(klōn) [Gr. klōn young shoot or twig] 1. one of a group of genetically identical (barring mutation) cells or organisms derived asexually from a single common ancestor. 2. a DNA population derived from a single molecule by recombinant DNA technology. 3. to establish such a progeny or population. clonal adj
Medical dictionary. 2011.