- cholic acid
- A family of steroids comprising the bile acids (or salts), generally in conjugated form ( e.g., glycocholic and taurocholic acid s). Chemically, cholic acid s are cholan-24-oic (cholanic) acids (the terminal C24 of cholane becoming a —COOH group); biologically, cholic acid s are derived from cholesterol (a cholestane derivative) and display varying degrees of oxidation (OH groups) and orientation at positions 3, 7, and 12. It is these oxidations and orientations that distinguish the several c.; e.g., c. is 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, deoxycholic acid is 3α,12α-dihydroxy-5β-cholanic acid. C. is a naturally occurring detergent that aids in the digestion of fats. SYN: cholalic acid, cholanic acid.
* * *cho·lic acid .kō-lik- n a crystalline bile acid C24H40O5
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* * *cho·lic ac·id (koґlik) 1. one of the primary bile acids, usually occurring conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion. 2. any of the substituted derivatives of cholic acid collectively constituting the bile acids.
Medical dictionary. 2011.