cholic acid

cholic acid
A family of steroids comprising the bile acids (or salts), generally in conjugated form ( e.g., glycocholic and taurocholic acid s). Chemically, cholic acid s are cholan-24-oic (cholanic) acids (the terminal C24 of cholane becoming a —COOH group); biologically, cholic acid s are derived from cholesterol (a cholestane derivative) and display varying degrees of oxidation (OH groups) and orientation at positions 3, 7, and 12. It is these oxidations and orientations that distinguish the several c.; e.g., c. is 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, deoxycholic acid is 3α,12α-dihydroxy-5β-cholanic acid. C. is a naturally occurring detergent that aids in the digestion of fats. SYN: cholalic acid, cholanic acid.

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cho·lic acid .kō-lik- n a crystalline bile acid C24H40O5

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cho·lic ac·id (koґlik) 1. one of the primary bile acids, usually occurring conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion. 2. any of the substituted derivatives of cholic acid collectively constituting the bile acids.

Medical dictionary. 2011.

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  • Cholic acid — IUPAC name (R) 4 ((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R) 3,7 …   Wikipedia

  • Cholic acid — Cholic Chol ic, Cholinic Cho*lin ic, a. [Gr. ?, from ? bile.] (Physiol. Chem.) Pertaining to, or obtained from, the bile. [1913 Webster] {Cholic acid} (Chem.), a complex organic acid found as a natural constituent of taurocholic and glycocholic… …   The Collaborative International Dictionary of English

  • cholic acid — [kō′lik] n. [< Gr cholikos < cholē, bile: see CHOLERA] an acid, C24H40O5, found in the bile, generally in combination with amino acids …   English World dictionary

  • cholic acid — cholio rūgštis statusas T sritis chemija apibrėžtis Steroidinė tulžies rūgštis. atitikmenys: angl. cholic acid rus. холевая кислота …   Chemijos terminų aiškinamasis žodynas

  • cholic acid — /koʊlɪk ˈæsəd/ (say kohlik asuhd) noun a steroidal bile acid, C23H39O3.COOH. {cholic from Greek cholikos of bile} …  

  • cholic acid — noun an insoluble crystalline acid present in bile • Hypernyms: ↑bile acid …   Useful english dictionary

  • cholic acid — noun Etymology: Greek cholikos bilious, from cholē Date: 1846 a crystalline bile acid C24H40O5 …   New Collegiate Dictionary

  • cholic acid — /koh lik, kol ik/ 1. Biochem. a bile acid, C24H40O5, related to the sex hormones and cholesterol. 2. the commercial form of this compound, obtained from beef bile, used chiefly in the manufacture of drugs and in research. [1840 50; < Gk cholikós… …   Universalium

  • cholic acid — noun a steroidal bile acid, CHO, derived from cholesterol …   Wiktionary

  • cholic acid — cholalic acid; see bile acids …   The new mediacal dictionary

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