antisense strand

antisense strand
the strand of a double-stranded nucleic acid that is complementary to the sense strand, in DNA being thus the template on which the mRNA is synthesized. Cf. sense s. See also antisense RNA, under RNA.

Medical dictionary. 2011.

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  • Antisense DNA — In double stranded DNA, only one strand codes for the RNA that is translated into protein. The strand that does not do so is called the antisense strand. Another way of defining antisense DNA is that it is the strand of DNA that does not carry… …   Medical dictionary

  • antisense — See a. DNA, a. RNA. * * * an·ti·sense an .tī .sens, an ti adj having a sequence complementary to a segment of genetic material specif of, being, relating to, or possessing a sequence of DNA or RNA that is complementary to and pairs with a… …   Medical dictionary

  • Antisense therapy — is a form of treatment for genetic disorders or infections.When the genetic sequence of a particular gene is known to be causative of a particular disease, it is possible to synthesize a strand of nucleic acid (DNA, RNA or a chemical analogue)… …   Wikipedia

  • Antisense RNA — (aRNA) is single stranded RNA that is complementary to a messenger RNA (mRNA) strand transcribed within a cell. Antisense RNA may be introduced into a cell to inhibit translation of a complementary mRNA by base pairing to it and physically… …   Wikipedia

  • strand — In microbiology, a filamentous or threadlike structure. anticoding s. the s. of duplex DNA which is used as a template for the synthesis of mRNA. SYN: antisense s.. antiparallel s. a macromolecular s. that is oriented in the opposite direction of …   Medical dictionary

  • Antisense RNA — The non coding strand complementary to a coding sequence of messenger RNA (mRNA), a molecule involved in translating genetic instructions into proteins. * * * (asRNA) an RNA molecule transcribed off the coding, rather than the template, strand of …   Medical dictionary

  • Antisense drug — A medication containing part of the non coding strand of messenger RNA (mRNA), a key molecule involved in the translation of DNA into protein. Antisense drugs hybridize with and inactivate mRNA. This stops a particular gene from producing the… …   Medical dictionary

  • antisense DNA — One of the two strands of double stranded DNA, usually that which is complementary (hence anti ) to the mRNA, i.e. the non transcribed strand. However, there is not universal agreement on this convention, and the preferred designations are coding …   Glossary of Biotechnology

  • antisense — In general the complementary strand of a coding sequence of DNA or of mRNA. Antisense RNA hybridizes with and inactivates mRNA …   Dictionary of molecular biology

  • antisense — /an tee sens , an tuy /, adj. of or pertaining to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic engineering to regulate genetic expression of a trait. [1985… …   Universalium

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