Antisense RNA

Antisense RNA
The non-coding strand complementary to a coding sequence of messenger RNA (mRNA), a molecule involved in translating genetic instructions into proteins.

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(asRNA) an RNA molecule transcribed off the coding, rather than the template, strand of DNA, and thus complementary to the sense (messenger) RNA; hybridization between the sense and antisense RNA molecules prevents translation of the mRNA in bacteria. In vitro, antisense RNA can be used to inhibit intranuclear RNA processing in eukaryotic cells.

Medical dictionary. 2011.

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  • Antisense RNA — (aRNA) is single stranded RNA that is complementary to a messenger RNA (mRNA) strand transcribed within a cell. Antisense RNA may be introduced into a cell to inhibit translation of a complementary mRNA by base pairing to it and physically… …   Wikipedia

  • antisense RNA — antisense RNA. См. антисмысловая РНК. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Antisense-RNA — Translationshemmung durch Antisense RNA Die Antisense RNA (aRNA) ist eine einzelsträngige RNA, die komplementär zur Messenger RNA (mRNA) ist. Die mRNA wird vom nicht kodierenden Strang (Matrizenstrang) der DNA transkribiert. Wird auch der… …   Deutsch Wikipedia

  • antisense RNA — A single stranded RNA with a base sequence complementary to a segment of another RNA molecule that can specifically bind to the target RNA and inhibit its activity …   Dictionary of microbiology

  • antisense RNA — An RNA sequence that is complementary to all or part of a functional mRNA molecule, to which it binds, blocking its translation …   Glossary of Biotechnology

  • Antisense RNA — …   Википедия

  • RNA interference — (RNAi) is a mechanism that inhibits gene expression at the stage of translation or by hindering the transcription of specific genes. RNAi targets include RNA from viruses and transposons (significant for some forms of innate immune response), and …   Wikipedia

  • Antisense therapy — is a form of treatment for genetic disorders or infections.When the genetic sequence of a particular gene is known to be causative of a particular disease, it is possible to synthesize a strand of nucleic acid (DNA, RNA or a chemical analogue)… …   Wikipedia

  • Antisense — (engl. etwa ‚Gegensinn‘) steht für: eine einzelsträngige RNA zur Regulation der Genexpression, siehe Antisense RNA die Leserichtung bei einzelsträngiger viraler DNA oder RNA, siehe Polarität (Virologie) Diese Seite ist eine Begrif …   Deutsch Wikipedia

  • Antisense-Oligonukleotid — Antisense Oligonukleotide sind kurzkettige synthetische Nukleinsäuren. Der Name nimmt darauf Bezug, dass ihre Basensequenz entgegengesetzt (und damit „entgegen dem ursprünglichen Sinn“ = anti sense) zu einer funktionalen mRNA ist. Während dem… …   Deutsch Wikipedia

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