basophilic stippling

basophilic stippling
the presence of basophilic granules, consisting of precipitated ribosomal RNA, in the cytoplasm of erythrocytes, seen in conditions of defective heme synthesis (such as β-thalassemia) and in lead poisoning. Called also punctate basophilia.

Medical dictionary. 2011.

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  • stippling — 1. A speckling of a blood cell or other structure with fine dots when exposed to the action of a basic stain, due to the presence of free basophil granules in the cell protoplasm. SYN: punctate basophilia. 2. An orange peel appearance of t …   Medical dictionary

  • stippling — noun ( s) 1. : a stippled effect 2. : a spotted condition (as in basophilic red blood corpuscles, the retina in diseases of the eye, X rays of the lungs, bones) …   Useful english dictionary

  • punctate basophilia — basophilic stippling …   Medical dictionary

  • Lead poisoning — Classification and external resources An X ray demonstrating the characteristic finding of lead poisoning, dense metaphyseal lines. ICD 10 T …   Wikipedia

  • basoerythrocyte — A red blood cell that manifests changes of basophilic degeneration, such as basophilic stippling, punctate basophilia, or basophilic granules …   Medical dictionary

  • Inclusion body — Inclusion bodies are nuclear or cytoplasmic aggregates of stainable substances, usually proteins. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. Inclusion… …   Wikipedia

  • Reactive lymphocyte — surrounded by red blood cells. Reactive lymphocytes are lymphocytes that become large as a result of antigen stimulation. Typically they can be more than 30 µm in diameter with varying size and shape. The nucleus of a reactive lymphocyte can be… …   Wikipedia

  • Hepatocyte — [ thumb|300px|Sinusoid of a rat liver with fenestrated endothelial cells. Fenestrae are approx 100 nm diameter, and the sinusoidal width 5 µm. Scanning electron micrograph by Robin Fraser, University of Otago.] Hepatocytes make up 70 80% of the… …   Wikipedia

  • Sideroblastic anemia — * With lead poisoning, see coarse basophilic stippling of red blood cells on peripheral blood smear * Specific test: Prussian Blue stain of RBC in marrow. Shows ringed sideroblasts.TreatmentOccasionally, the anemia is so severe that support with… …   Wikipedia

  • Codocyte — This article is about the abnormally shaped red blood cell. For the endocrinology concept, see target cell. Codocytes, also known as target cells or Mexican hat cells[1],[2] are red blood cells that have the appearance of a shooting target with a …   Wikipedia

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