sterol esterase

sterol esterase
ster·ol es·ter·ase (sterґol esґtər-ās) [EC 3.1.1.13] an enzyme of the hydrolase class that catalyzes the cleavage of cholesterol and other sterol esters and triglycerides. Deficiency of the lysosomal enzyme causes the allelic autosomal recessive disorders Wolman disease and cholesteryl ester storage disease. Called also acid lipase and cholesterol esterase.

Medical dictionary. 2011.

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  • Sterol esterase — In enzymology, a sterol esterase (EC number|3.1.1.13) is an enzyme that catalyzes the chemical reaction:a steryl ester + H2O ightleftharpoons a sterol + a fatty acidThus, the two substrates of this enzyme are steryl ester and H2O, whereas its two …   Wikipedia

  • cholesterol esterase — cho·les·ter·ol es·ter·ase (kə lesґtər ol esґtər ās) sterol esterase …   Medical dictionary

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • Gallensalz-aktivierte Lipase — Masse/Länge Primärstruktur 722 Aminosäuren …   Deutsch Wikipedia

  • EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • acid lipase — ac·id li·pase (as″id liґpās) 1. sterol esterase. 2. a lipase with an acid pH optimum …   Medical dictionary

  • cholesteryl ester storage disease — (CESD) a relatively mild lysosomal storage disease caused by deficiency of the lysosomal sterol esterase; hepatomegaly may be the only clinical abnormality; hyperbetalipoproteinemia is common, and there is often severe premature atherosclerosis;… …   Medical dictionary

  • Wolman disease — a lysosomal storage disease caused by deficiency of the lysosomal sterol esterase, with onset in early infancy and death before one year of age. Clinical features include hepatosplenomegaly, steatorrhea, abdominal distention, anemia, inanition,… …   Medical dictionary

  • Tocopherol — Tocopherols (or TCP) are a class of chemical compounds of which many have vitamin E activity. It is a series of organic compounds consisting of various methylated phenols. Because the vitamin activity was first identified in 1936 from a dietary… …   Wikipedia

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