Darier sign

Darier sign
urtication and itching occurring on rubbing the lesions of urticaria pigmentosa.

Medical dictionary. 2011.

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  • Darier's sign — is a change observed after stroking the skin of a person with systemic mastocytosis or urticaria pigmentosa. In general, the skin becomes swollen, itchy and red. This is a result of compression of mast cells, which are hyperactive in these… …   Wikipedia

  • Darier disease sign — Da·rier disease, sign (dah re aґ) [Jean Ferdinand Darier, French dermatologist, 1856–1938] see under disease and sign …   Medical dictionary

  • Sign — Any abnormality that indicates a disease process, such as a change in appearance, sensation, or function, that is observed by a physician when evaluating a patient. * * * 1. Any abnormality indicative of disease, discoverable on examination of… …   Medical dictionary

  • Darier — Jean F., French dermatologist, 1856–1938. See D. disease, D. sign …   Medical dictionary

  • Ferdinand-Jean Darier — Born 26 April 1856(1856 04 26) Budapest, Hungary Died 1938 (aged 81–82) Paris, France[citation needed] …   Wikipedia

  • Nikolsky's sign — is a clinical dermatological sign, named after the Russian physician Pyotr Nikolsky (1858–1940). The sign is positive when slight rubbing of the skin results in exfoliation of the outermost layer.[1][2][3] …   Wikipedia

  • Crowe sign — The Crowe sign or Crowe s sign is the presence of axillary (armpit) freckling in people with neurofibromatosis type I (von Recklinghausen s disease). These freckles occur in up to 30% of people with the disease and their presence is one of seven… …   Wikipedia

  • Asboe–Hansen sign — The Asboe Hansen sign (also known as indirect Nikolsky sign [1] or Nikolsky II sign [1]) refers to the extension of a blister to adjacent unblistered skin when pressure is put on the top of the bulla.[2] See also Nikolsky s sign List of cutaneous …   Wikipedia

  • Wheal — A raised, itchy (pruritic) area of skin that is almost always an overt sign of allergy. Not all wheals are alike. They may be redder or paler than the skin around them. They may vary in configuration and may be rounded or flat topped. Wheals… …   Medical dictionary

  • urticaria pigmentosa — the most common form of mastocytosis, seen primarily in children, characterized by multiple persistent small, hyperpigmented, pruritic macules and papules. The usual site is on the trunk, although some cases are on the limbs, head, or neck.… …   Medical dictionary

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