antibody screening

antibody screening
a method of determining the presence and amount of anti-HLA antibodies in the serum of a potential allograft recipient: aliquots of the recipient's serum are mixed with a panel of leukocytes from well-characterized cell donors and complement is added. Reaction between the recipient's pre-existing antibody and specific antigen in the donor cells leads to cell lysis; the percentage of different cells lysed provides a rough measure of the sensitization of the recipient (referred to as the panel reactive antibody).

Medical dictionary. 2011.

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