ceramide

ceramide
Generic term for a class of sphingolipid, N-acyl (fatty acid) derivatives of a long chain base or sphingoid such as sphinganine or sphingosine; e.g., CH3(CH2)12CH=CH—CHOH—CH(CH2OH)—NH—CO—R, where R is the fatty-acyl residue, attached in this example to 4-sphingenine (sphingosine) in amide linkage. Ceramides accumulate in individuals with Farber disease.
- c. dihexoside the accumulated glycolipid noted in glycolipid lipidosis.
- c. lactosidase a hydrolytic enzyme (a β-galactosidase) that acts on c. lactoside, producing glucosylceramide and galactose. A deficiency of this enzyme can result in c. lactoside liposis. Cf.:cytolipin.
- c. lactoside a lactosylceramide that accumulates in individuals with ceremide lactoside liposis. Cf.:cytolipin.
- c. saccharide SYN: glycosphingolipid.

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cer·amide 'sir-ə-.mīd n any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

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cer·a·mide (serґə-mīd) the basic unit of the sphingolipids; it is sphingosine, or a related base, attached via its amino group to a long chain fatty acyl group. Ceramides are accumulated abnormally in Farber disease. Called also N-acylsphingosine.

Medical dictionary. 2011.

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  • Ceramide — Céramide Les céramides sont une famille de lipides. Ils sont issus de la réaction d amidification de la sphingosine et d un acide gras. Ils peuvent conduire à la synthèse de sphingolipides par une réaction d addition sur la fonction alcool… …   Wikipédia en Français

  • céramide — ● céramide nom masculin Molécule organique, formée par la combinaison d un acide gras à chaîne longue et d un alcool aminé, constituant principal de certains lipides complexes des membranes cellulaires ainsi que de la myéline du système nerveux.… …   Encyclopédie Universelle

  • Ceramide — General chemical structure of sphingolipids. When the substituent (R) in this structure is H, the resulting molecule is a ceramide …   Wikipedia

  • Ceramide — Allgemeine Struktur der Ceramide. Der Rest R steht für die Kohlenwasserstoffkette einer Fettsäure. Als Ceramide bezeichnet man eine zu den Lipiden zählende Untergruppe der Sphingolipide. Sie bestehen aus einem Sphingosinmolekül, das durch eine… …   Deutsch Wikipedia

  • ceramide — ceramidas statusas T sritis chemija apibrėžtis Sfingozino ir riebalų rūgšties amidas. atitikmenys: angl. ceramide rus. церамид …   Chemijos terminų aiškinamasis žodynas

  • Ceramide kinase — Identifiers EC number 2.7.1.138 CAS number 123175 68 8 …   Wikipedia

  • Ceramide glucosyltransferase — (or glucosylceramide synthase) is a glucosyltransferase enzyme involved in the production of glucosylceramide. It is classified under EC 2.4.1.80. It is inhibited by miglustat. See also Glucosylceramide External links MeSH… …   Wikipedia

  • Ceramide cholinephosphotransferase — Identifiers EC number 2.7.8.3 CAS number 9026 14 6 …   Wikipedia

  • ceramide trihexoside — any of a specific family of glycosphingolipids of composition galactose galactose glucose ceramide; due to deficiency of α galactosidase A activity, they accumulate abnormally in plasma and tissues in Fabry disease …   Medical dictionary

  • ceramide cholinephosphotransferase — cer·a·mide cho·line·phos·pho·trans·fer·ase (serґə mīd ko″lēn fos″fo transґfər ās) [EC 2.7.8.3] an enzyme of the transferase class that catalyzes the transfer of a phosphorylated choline group from CDPcholine… …   Medical dictionary

  • ceramide — noun Etymology: cerebroside + amide Date: 1958 any of various lipids formed by linking a fatty acid to sphingosine and found widely but in small amounts in plant and animal tissue …   New Collegiate Dictionary

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