chromatin remodeling

chromatin remodeling
alterations in chromatin structure that affect the behavior of the chromosomes, often specifically changes in nucleosome structure causing regions adjacent to actively transcribed genes to become hypersensitive to cleavage by nucleases, as by disruption of DNA–histone contacts, releasing the histones, or by sliding of nucleosomes along the DNA.

Medical dictionary. 2011.

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  • Chromatin remodeling — is the enzyme assisted movement of nucleosomes on DNA. This is performed by chromatin remodeling complexes like SWI/SNF[1] (human, yeast), RSC (yeast) and Imitation SWI complexes (fly). At the core of a chromatin remodeling complex is an ATPase… …   Wikipedia

  • Chromatin structure remodeling (RSC) complex — AFM images showing single RSC complexes bound to dsDNA. The center and right images show RSC generated DNA loops (bar = 50 nm). RSC is a 17 subunit complex with the capacity to remodel the structure of chromatin. It exhibits a DNA dependent… …   Wikipedia

  • Chromatin Structure Remodeling (RSC) Complex — complex and is essential for mitotic growth.cite journal | author = Cairns BR, Lorch Y, Li Y, Zhang M, Lacomis L, Erdjument Bromage H, Tempst P, Du J, Laurent B, Kornberg RD | title = RSC, an essential, abundant chromatin remodeling complex |… …   Wikipedia

  • Chromatin — The major structures in DNA compaction; DNA, the nucleosome, the 10nm beads on a string fibre, the 30nm fibre and the metaphase chromosome Chromatin is the combination of DNA and proteins that make up the contents of the nucleus of a cell. The… …   Wikipedia

  • RSF1 — Remodeling and spacing factor 1, also known as RSF1, is a human gene.cite web | title = Entrez Gene: RSF1 remodeling and spacing factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=51773| accessdate =… …   Wikipedia

  • CHAF1A — Chromatin assembly factor 1, subunit A (p150), also known as CHAF1A, is a human gene.cite web | title = Entrez Gene: CHAF1A chromatin assembly factor 1, subunit A (p150)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Nucleosome — Nucleosomes are the basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound around a histone protein core.[1] This structure is often compared to thread wrapped around a spool.[2] Nucleosomes form the fundamental repeating …   Wikipedia

  • SMARCA5 — SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5, also known as SMARCA5, is a human gene.cite web | title = Entrez Gene: SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of… …   Wikipedia

  • SMARCC1 — SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1, also known as SMARCC1, is a human gene.cite web | title = Entrez Gene: SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of… …   Wikipedia

  • SMARCC2 — SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, also known as SMARCC2, is a human gene.cite web | title = Entrez Gene: SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of… …   Wikipedia

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