Prausnitz-KÑŒstner reaction
- Prausnitz-KÑŒstner reaction
- a type I hypersensitivity reaction produced in a nonatopic subject by intradermal injection of serum from an atopic subject, followed 12 or more hours later by an injection of antigen into the same site; the presence of specific IgE antibody in the transferred serum results in a classic wheal and flare reaction to the antigen. Once the standard method of demonstrating IgE, this test is no longer used because of the risk of transmitting hepatitis and because serum IgE can now be measured by in vitro assays, e.g., RAST and RIST. Called also P-K r. or test and Prausnitz-KÑŒstner test.
Medical dictionary.
2011.
Look at other dictionaries:
Prausnitz-KÑŒstner reaction (test) — Praus·nitz KÑŒst·ner reaction (test) (prousґnits kēstґner) [Otto Carl Willy Prausnitz, German hygienist, 1876–1963; Heinz KÑŒstner, German gynecologist, 1897–1963] see under reaction … Medical dictionary
Prausnitz-KÑŒstner antibodies — cytotropic IgE antibodies responsible for cutaneous anaphylaxis; see Prausnitz KÑŒstner reaction, under reaction … Medical dictionary
Prausnitz-KÑŒstner test — see under reaction … Medical dictionary
P-K reaction — Prausnitz KÑŒstner r … Medical dictionary
passive transfer test — see Prausnitz KÑŒstner reaction, under reaction … Medical dictionary
P-K test — see Prausnitz KÑŒstner reaction, under reaction … Medical dictionary
