sphingolipid activator protein

sphingolipid activator protein
(SAP) any of a group of nonenzyme lysosomal proteins that stimulate the actions of specific lysosomal hydrolases by binding and solubilizing their sphingolipid substrates; it includes the saposins and GM2 activator protein (qq.v.).

Medical dictionary. 2011.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • GM2 activator protein — a sphingolipid activator protein that binds GM2 ganglioside and related glycosphingolipids and presents them to hexosaminidase A for cleavage; it is necessary for enzyme activity. Deficiency results in GM2 gangliosidosis, AB variant …   Medical dictionary

  • Prosaposin — PDB rendering based on 1m12 …   Wikipedia

  • sap — The juice or tissue fluid of a living organism. cell s. contents of vacuoles. nuclear s. SYN: karyolymph. * * * sensory action potential; serum acid phosphatase; serum alkaline phosphatase; serum amyloid P; shrimp alkaline phosphatase; situs… …   Medical dictionary

  • GM2 g. AB variant — a GM2 gangliosidosis caused by mutation in the GM2Agene (locus: 5q31.3 q33.1), which encodes GM2 activator protein, a sphingolipid activator protein necessary for hexosaminidase A activity; this variant is clinically identical to infantile Tay… …   Medical dictionary

  • SAP — • sensory action potential; • serum acid phosphatase; • serum alkaline phosphatase; • serum amyloid P; • shrimp alkaline phosphatase; • situs ambiguus with polysplenia; • sphingolipid activator protein; • stable angina pectoris; • Staphylococcus… …   Dictionary of medical acronyms & abbreviations

  • ЛЕЙКОДИСТРОФИЯ МЕТАХРОМАТИЧЕСКАЯ — мед. Метахроматическая лейкодистрофия наследственная болезнь накопления (продукты распада липидов окрашиваются метахроматически) лейкоэнцефалопатия в сочетании с диффузной демиелинизацией ЦНС. В зависимости от характера генетического дефекта,… …   Справочник по болезням

  • SAPD — short action potential duration; signal averaged P wave duration; sphingolipid activator protein deficiency …   Medical dictionary

  • SAPD — • short action potential duration; • signal averaged P wave duration; • sphingolipid activator protein deficiency …   Dictionary of medical acronyms & abbreviations

  • Hexosaminidase — β N acetylhexosaminidase Hexosaminidase A (Hex A) Identifiers EC number 3.2.1.52 …   Wikipedia

  • Sortilin 1 — Sortilin 1, also known as SORT1, is a human gene.cite web | title = Entrez Gene: SORT1 sortilin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=6272| accessdate = ] PBB Summary section title = summary… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”