myeloma protein

myeloma protein
any of the pathological immunoglobulin proteins or fragments, such as M component and Bence Jones protein, secreted by myeloma cells.

Medical dictionary. 2011.

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  • Myeloma protein — is usually a monoclonal antibody or immunoglobulin fragment that is produced by malignant myeloma cells, or plasma cells. Other terms for this protein is M protein, spike protein,or paraprotein. This proliferation of the myeloma protein has… …   Wikipedia

  • protein — proteinaceous /proh tee nay sheuhs, tee i nay /, proteinic, proteinous, adj. /proh teen, tee in/, n. 1. Biochem. any of numerous, highly varied organic molecules constituting a large portion of the mass of every life form and necessary in the… …   Universalium

  • Myeloma — A tumor of antibody producing cells, called plasma cells, that are normally found in the bone marrow. * * * 1. A tumor composed of cells derived from hemopoietic tissues of the bone marrow. 2. A plasma cell tumor. [myelo + G. oma, tumor] Bence… …   Medical dictionary

  • Protein electrophoresis — In chemistry and medicine, protein electrophoresis (a.k.a. Immunoelectrophoresis) is a method of analysing a mixture of proteins by means of gel electrophoresis, mainly in blood serum (blood plasma is not suitable). Before the widespread use of… …   Wikipedia

  • myeloma kidney — renal changes occurring in multiple myeloma, due to filtration of large amounts of Bence Jones protein; they include tubular atrophy with multinucleated giant cells in the tubule walls and interstitium, as well as formation of myeloma casts (see… …   Medical dictionary

  • Protein — A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein. Proteins are required for the structure, function, and regulation of the body s… …   Medical dictionary

  • myeloma cast — a urinary cast containing Bence Jones protein and desquamated cells of the tubular epithelium, seen with multiple myeloma in the condition known as myeloma kidney …   Medical dictionary

  • myeloma — multiple myeloma; = myelomatosis; n. a malignant disease of the bone marrow, characterized by two or more of the following criteria: 1) the presence of an excess of abnormal malignant plasma cells in the bone marrow; 2) typical lytic deposits in… …   The new mediacal dictionary

  • multiple myeloma — Pathol. a malignant plasma cell tumor of the bone marrow that destroys bone tissue. [1895 1900; MYEL + OMA] * * * ▪ pathology also called  plasma cell myeloma  or  myelomatosis        malignant proliferation (tumour) of cells within the bone… …   Universalium

  • Multiple myeloma — Classification and external resources Micrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H E stain ICD …   Wikipedia

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