- GTPase-activating protein
- a protein that stimulates the GTPase activity of a GTP-binding protein, resulting in the conversion of the protein to its inactive form.
Medical dictionary. 2011.
GTPase-activating protein
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GTPase activating protein — GTPase Activating Proteins, or GAPs, or GTPase Accelerating Proteins is a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity with the result of terminating the signaling event.GAPs… … Wikipedia
GTPase activating protein — GAP (eng: GTPase activating proteins) sind Proteine, die auf G Proteine derart einwirken, dass diese ihr gebundenes GTP unter Abspaltung eines Phosphat Restes zu GDP hydrolysieren. In den meisten Fällen wird dadurch das Zielprotein desaktiviert,… … Deutsch Wikipedia
GTPase-activating protein — Originally purified as a 125 kD protein from bovine brain (1044 amino acids) ; stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a… … Dictionary of molecular biology
IQ motif containing GTPase activating protein — (IQGAP) is a carrier protein.It is associated with the Rho GTP binding protein.Genes*, Gene|IQGAP2, Gene|IQGAP3 … Wikipedia
GTPase — GTPases (singular GTPase) are a large family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). The GTP binding and hydrolysis takes place in the highly conserved G domain common to all GTPases. They help GTP binding… … Wikipedia
GTPase — Die Mitglieder der Proteinfamilie der kleinen GTPasen sind kleine Proteine, die durch die alternierende Bindung der Nukleotide GDP oder GTP als molekulare „Schalter“ in Signaltransduktionsketten fungieren. Sie haben eine molare Masse von 20 25… … Deutsch Wikipedia
RAS p21 protein activator 1 — or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120 kDa cytosolic human protein that provides two principal activities: * Inactivation of Ras from its active GTP bound form to its unactive GDP bound form by enhancing the… … Wikipedia
GTP-binding protein regulators — regulate G proteins in several different ways. Small GTPases act as molecular switches in signaling pathways, which act to regulate functions of other proteins. They are active or ON when it is bound to GTP and inactive or OFF when bound to GDP.… … Wikipedia
Rab (Protein) — Die Familie der Rab Proteine („Ras related in brain“) gehört zur Ras Superfamilie monomerer G Proteine (GTPasen) und ist in Eukaryoten zu großen Teilen konserviert. Die rund 70 beim Menschen bekannten Rab Proteine spielen eine Rolle bei der… … Deutsch Wikipedia
SUMO protein — Small Ubiquitin like Modifier or SUMO proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMOylation is a post translational modification involved in various … Wikipedia
