polysialic acid

polysialic acid
poly·si·a·lic ac·id (pol″si-alґik) large hydrated polysaccharide similar to K1 of Escherichia coli.

Medical dictionary. 2011.

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  • Polysialic acid — is an unusual posttranslational modification that occurs on neural cell adhesion molecules (NCAM). Polysialic acid is considerably anionic. This strong negative charge gives this modification the ability to change the proteins surface charge and… …   Wikipedia

  • polysialic acid — Potential regulator of cell cell interactions. Polysialic acid chains in glycoproteins may have negative regulatory effects on cell cell contact. Thus the low PSA form of NCAM is thought to promote cell cell contact and enhance fasciculation… …   Dictionary of molecular biology

  • Polysialic-acid O-acetyltransferase — In enzymology, a polysialic acid O acetyltransferase (EC number|2.3.1.136) is an enzyme that catalyzes the chemical reaction:acetyl CoA + an alpha 2,8 linked polymer of sialic acid ightleftharpoons CoA + polysialic acid acetylated on O 7 or O… …   Wikipedia

  • polysialic acid — noun A polymeric form of sialic acid that is involved in cell adhesion …   Wiktionary

  • polysialic — adjective Of or pertaining to polysialic acid or its derivatives …   Wiktionary

  • PSA-NCAM — polysialic acid neuronal cell adhesion molecule …   Medical dictionary

  • PSA-NCAM — • polysialic acid neuronal cell adhesion molecule …   Dictionary of medical acronyms & abbreviations

  • Nerve guidance conduit — A nerve guidance conduit (also referred to as an artificial nerve conduit or artificial nerve graft, as opposed to an autograft) is an artificial means of guiding axonal regrowth to facilitate nerve regeneration and is one of several clinical… …   Wikipedia

  • ST8SIA2 — ST8 alpha N acetyl neuraminide alpha 2,8 sialyltransferase 2, also known as ST8SIA2, is a human gene.cite web | title = Entrez Gene: ST8SIA2 ST8 alpha N acetyl neuraminide alpha 2,8 sialyltransferase 2| url =… …   Wikipedia

  • Neural cell adhesion molecule — 1 PDB rendering based on 1epf …   Wikipedia

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