carbidopa

A dopa decarboxylase inhibitor which does not enter the brain used in conjunction with levodopa in the treatment of Parkinson disease to reduce L-dopa doses and reduce side effect s.

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car·bi·do·pa .kär-bə-'dō-pə n a drug C₁₀H₁₄N₂O₄·H₂O that inhibits decarboxylation of L-dopa in tissues outside the brain and that is administered with, L-dopa in the treatment of Parkinson's disease to increase the amount of, L-dopa available for transport to the brain

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car·bi·do·pa (kahr″bĭ-doґpə) [USP] an inhibitor of the decarboxylation of peripheral levodopa to dopamine, which does not penetrate the central nervous system. When given with levodopa, carbidopa produces higher brain concentrations of dopamine with lower doses of levodopa, thus lessening the side effects seen with higher doses. It is used orally, in conjunction with levodopa, as an antiparkinsonian agent.