phospholipase A2

phospholipase A2
[EC 3.1.1.4] any esterase that catalyzes the hydrolysis of the central acyl group from a membrane phospholipid, generating a free fatty acid and a lysophospholipid; this reaction is important in the digestion of dietary phospholipids, and it liberates arachidonic acid for a variety of processes, such as platelet activation. The enzyme occurs in various forms in all mammalian tissues and in snake and bee venoms. EC nomenclature for the enzyme specifically hydrolyzing phosphatidylinositol is phosphatidylinositol deacylase.

Medical dictionary. 2011.

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