phosphatidylinositol 45-bisphosphate

phosphatidylinositol 45-bisphosphate
(PIP2) a polyphosphoinositide occurring as a minor constituent of the plasma membrane and involved in calcium-mediated responses to hormones; its breakdown to the second messengers diacylglycerol and inositol 1,4,5-triphosphate is a primary event resulting in increases in intracellular calcium.

Medical dictionary. 2011.

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  • Phosphatidylinositol — (abbreviated PtdIns, or PI) is a minor phospholipid component in the cytosolic side of eukaryotic cell membranes. Being an amphiphile, this molecule possesses polymorphic behaviour, that is currently a topic of research in academic study.… …   Wikipedia

  • Phosphatidylinositol bisphosphate — may refer to: * Phosphatidylinositol (3,4) bisphosphate * Phosphatidylinositol (3,5) bisphosphate * Phosphatidylinositol (4,5) bisphosphate …   Wikipedia

  • Phosphatidylinositol (3,5)-bisphosphate — (PtdIns(3,5) P 2) is a minor phospholipid component of cell membranes, yet important in distinguishing cell compartments. The generation of PtdIns(3,5) P 2 in internal membranes by the lipid kinase PIKfyve recruits a number of important proteins… …   Wikipedia

  • Phosphatidylinositol (3,4)-bisphosphate — (PtdIns(3,4) P 2) is a minor phospholipid component of cell membranes, yet an important second messenger. The generation of PtdIns(3,4) P 2 at the plasma membrane activates a number of important cell signaling pathways. PtdIns(3,4) P 2 is… …   Wikipedia

  • Phosphatidylinositol (3,4,5)-trisphosphate — (PtdIns(3,4,5) P 3) commonly abbreviated to PIP3 is the product of the class I phosphoinositide 3 kinases (PI 3 kinases) activity on phosphatidylinositol (4,5) bisphosphate. PtdIns(3,4,5) P 3 is dephophosphorylated by the phosphatase, PTEN on the …   Wikipedia

  • Phosphatidylinositol 4-phosphate — (PtdIns4 P ) is a precursor of Phosphatidylinositol (4,5) bisphosphate. PtdIns4 P is prevalent in the membrane of the Golgi apparatus.In the Golgi apparatus, PtdIns4 P binds to the GTP binding protein ARF and to effector proteins, including four… …   Wikipedia

  • Phosphatidylinositol-3,4-bisphosphate 4-phosphatase — In enzymology, a phosphatidylinositol 3,4 bisphosphate 4 phosphatase (EC number|3.1.3.66) is an enzyme that catalyzes the chemical reaction:1 phosphatidyl myo inositol 3,4 bisphosphate + H2O ightleftharpoons 1 phosphatidyl 1D myo inositol 3… …   Wikipedia

  • Phosphatidylinositol-4,5-bisphosphate 3-kinase — In enzymology, a phosphatidylinositol 4,5 bisphosphate 3 kinase (EC number|2.7.1.153) is an enzyme that catalyzes the chemical reaction:ATP + 1 phosphatidyl 1D myo inositol 4,5 bisphosphate ightleftharpoons ADP + 1 phosphatidyl 1D myo inositol… …   Wikipedia

  • Phosphatidylinositol (4,5)-bisphosphate — chembox new ImageFile = Phosphatidylinositol 4,5 bisphosphate.jpg OtherNames = Formula = C47H85O19P3 PubChem = 5497157 MolarMass= 1047.09 CASNo = 245126 95 8 Density= MeltingPt= BoilingPt=Phosphatidylinositol (4,5) bisphosphate (PtdIns(4,5) P 2)… …   Wikipedia

  • Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase — In enzymology, a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase (EC number|3.1.3.67) is an enzyme that catalyzes the chemical reaction:phosphatidylinositol 3,4,5 trisphosphate + H2O ightleftharpoons phosphatidylinositol 4,5 bisphosphate + …   Wikipedia

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