Lucio phenomenon

Lucio phenomenon
a local exacerbation reaction occurring in Lucio leprosy. Initially there is ischemic necrosis of the epidermis due to necrotizing vasculitis of small blood vessels of the subpapillary plexus; next, small erythematous lesions erupt and have central necrosis; later, if the eschar is shed, ulceration can be seen, with eventual scar formation. Cf. erythema nodosum leprosum.

Medical dictionary. 2011.

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