extrinsic pathway of coagulation

extrinsic pathway of coagulation
the mechanism that produces fibrin following tissue injury, beginning with formation of an activated complex between tissue factor and activated factor VII and leading to activation of factor X, which induces the reactions of the common pathway of coagulation. See illustration. Cf. intrinsic p. of coagulation.

Medical dictionary. 2011.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • intrinsic pathway of coagulation — a sequence of reactions leading to fibrin formation, beginning with the contact activation of factor XII, followed by the sequential activation of factors XI and IX, and resulting in the activation of factor X, which in activated form initiates… …   Medical dictionary

  • common pathway of coagulation — the steps in the mechanism of coagulation from the activation of factor X through the conversion of fibrinogen to fibrin. See illustration. See also intrinsic p. of coagulation and extrinsic p. of coagulation …   Medical dictionary

  • Coagulation — This article is about blood clotting. For other meanings see Coagulation (disambiguation). Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis, the cessation of blood loss from a damaged vessel,… …   Wikipedia

  • Coagulation screen — A combination of screening laboratory tests, designed to provide rapid non specific information, which allows an initial broad categorization of haemostatic problems. The basic screen consists of: platelet count bleeding time for platelet… …   Wikipedia

  • coagulation pathways — see common p. of coagulation, extrinsic p. of coagulation, and intrinsic p. of coagulation. Coagulation pathway overview …   Medical dictionary

  • coagulation cascade — the series of steps beginning with activation of the intrinsic or extrinsic pathways of coagulation, or of one of the related alternative pathways, and proceeding through the common pathway of coagulation to the formation of the fibrin clot; each …   Medical dictionary

  • Tissue factor pathway inhibitor — (or TFPI) is a single chain polypeptide which can reversibly inhibit Factor Xa (Xa). While Xa is inhibited, the Xa TFPI complex can subsequently also inhibit the FVIIa TF complex.TFPI contributes significantly to the inhibition of Xa in vivo,… …   Wikipedia

  • Disseminated intravascular coagulation — or Disseminated intravascular coagulopathy Classification and external resources Micrograph showing a thrombotic microangiopathy, as may be seen in DIC. Kidney biopsy. PAS stain …   Wikipedia

  • Laboratory diagnosis of coagulation disorders — ▪ Table Laboratory diagnosis of coagulation disorders test factor evaluated prothrombin time extrinsic pathway partial thromboplastin time intrinsic pathway thrombin time fibrinogen conversion to fibrin fibrinogen fibrinogen concentration fibrin… …   Universalium

  • Tissue factor — Coagulation factor III (thromboplastin, tissue factor) PDB rendering based on 1ahw …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”