calmodulin

calmodulin
A small, ubiquitous eukaryotic protein that binds calcium ions, thereby becoming the agent for many of the cellular effects long ascribed to calcium ions. This calcium-protein complex binds to the apoenzyme, to form the holoenzyme, of certain phosphodiesterases; through these, or other as yet unknown mechanisms, the complex regulates adenylate and guanylate cyclase s, many kinases, phospholipase A2 activity, and other basic cellular functions. [calcium + modulate]

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cal·mod·u·lin .kal-'mäj-ə-lən n a calcium-binding protein that mediates cellular metabolic processes (as muscle-fiber contraction) by regulating the activity of specific calcium-dependent enzymes

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cal·mod·u·lin (kal-modґu-lin) a ubiquitous calcium-binding protein of eukaryotic cells that mediates a variety of cellular responses to calcium. The calcium-calmodulin complex acts as a messenger, affecting the activity of many enzymes and nonenzyme proteins, including the calcium pump, numerous specific protein kinases and cyclic nucleotide phosphodiesterases, spectrin, histones, and tubulin.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Calmodulin 1 — (phosphorylase kinase, delta) PDB rendering based on 1a29 …   Wikipedia

  • Calmodulin — Vorhandene Strukturdaten: s. UniProt Masse/Länge …   Deutsch Wikipedia

  • Calmodulin — Calmodulin, in allen Eukaryotenzellen vorhandenes, calciumbindendes Protein, das als Ca2+ Calmodulin Komplex verschiedene Enzyme aktiviert und so in das Stoffwechselgeschehen der Zelle eingreift …   Deutsch wörterbuch der biologie

  • calmodulin — calmodulin. См. кальмодулин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • calmodulin — [kal mä′jo͞o lin΄, kal mä′jəlin΄] n. [ CAL(CIUM) + MODUL(ATE) + IN1] a protein in nearly all cells that binds to calcium and regulates many important cell functions, as nerve impulse transmissions and muscle action …   English World dictionary

  • Calmodulin — [ http://www.pdb.org/pdb/static.do?p=education discussion/molecule of the month/pdb44 1.html more details...] ] Calmodulin (CaM) (an abbreviation for CALcium MODULated proteIN) is a calcium binding protein expressed in all eukaryotic cells. It… …   Wikipedia

  • Calmodulin — Cal|mo|du|lin [Kurzw. aus ↑ Calcium u. Modulation; ↑ in (3)], das; s, e: ein Protein aus 148 Aminosäuren, das als intrazellulärer Rezeptor für Calcium Ionen zahlreiche Ca abhängige Stoffwechselprozesse im Organismus steuert. * * * Calmodulin  … …   Universal-Lexikon

  • Calmodulin-binding proteins — are, as their name implies, proteins which bind calmodulin.Examples include:* Gap 43 protein (presynaptic)* Neurogranin (postsynaptic)* CaldesmonExternal links* …   Wikipedia

  • Calmodulin-lysine N-methyltransferase — ) is an enzyme that catalyzes the chemical reaction:S adenosyl L methionine + calmodulin L lysine ightleftharpoons S adenosyl L homocysteine + calmodulin N6 methyl L lysineThus, the two substrates of this enzyme are S adenosyl methionine and… …   Wikipedia

  • calmodulin — noun Etymology: calcium + modulate + 1 in Date: 1978 a calcium binding protein that mediates cellular metabolic processes (as the contraction of muscle fibers) by regulating the activity of calcium dependent enzymes …   New Collegiate Dictionary

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