calcineurin

calcineurin
A calcium-dependent serine-threonine phosphatase involved in T-cell signaling transcription; the reaction cascade in which it resides is referred to as the c. pathway. [calcium + G. neuron, nerve, + -in]

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cal·ci·neur·in (kal″sĭ-noorґin) a protein phosphatase that is specific for serine and threonine; it binds calmodulin and plays an important role in activation of T cells. See also calcineurin inhibitor, under inhibitor.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Calcineurin — Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • calcineurin — /kal si nū rin/ noun An enzyme which plays a role in many brain functions, abnormal levels of which are associated with schizophrenia ORIGIN: calcium, ↑neur with sfx in …   Useful english dictionary

  • Calcineurin — Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform, also known as PPP3CA, is a human gene.cite web | title = Entrez Gene: PPP3CA protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform| url =… …   Wikipedia

  • calcineurin inhibitor — any of a group of compounds that inhibit the action of calcineurin and are used as immunosuppressants …   Medical dictionary

  • calcineurin — Calmodulin stimulated protein phosphatase (EC 3.1.3.16), the major calmodulin binding protein in brain. Enzymic activity is inhibited by binding of immunophilin ligand complex (immunophilin alone does not bind) and therefore may play a part in… …   Dictionary of molecular biology

  • calcineurin — noun A protein phosphatase that stimulates the growth and differentiation of T cells …   Wiktionary

  • PP2B — Calcineurin Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • Protein-Phosphatase 2B — Calcineurin Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • Protein Phosphatase 2B — Calcineurin Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • CABIN1 — Calcineurin binding protein 1, also known as CABIN1, is a human gene.cite web | title = Entrez Gene: CABIN1 calcineurin binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=23523| accessdate =… …   Wikipedia

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