cadherin

cadherin
One of a class of integral-membrane glycoproteins that has a role in cell-cell adhesion and is important in morphogenesis and differentiation; E-c. is also known as uvomorulin and is concentrated in the belt desmosome in epithelial cells; N-c. is found in nerve, muscle, and lens cells helps maintain the integrity of neuronal aggregates; P-c. is expressed in placental and epidermal cells. [cell + adhere + -in]

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cad·he·rin (kad-hērґin) any of a family of over 80 calcium-dependent cell adhesion molecules, having in common the CAD domain of about 115 residues. Typically, they have 5 extracellular CAD domains (7 for protocadherins) connected to an intracellular C-terminal by a single hydrophobic sequence. Cell adhesion is by homophilic interaction.

Medical dictionary. 2011.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Cadherin — 1; E cadherin Größe 108 aa; 12,1 kDa Struktur Homodimer Bezeichner …   Deutsch Wikipedia

  • Cadherin — Cadherins are a class of type 1 transmembrane proteins. They play important roles in cell adhesion, ensuring that cells within tissues are bound together. They are dependent on calcium (Ca2+) ions to function, hence their name.The cadherin… …   Wikipedia

  • cadherin — noun Any of a class of transmembrane proteins important in maintaining tissue structure …   Wiktionary

  • VE-cadherin — Cadherin 5, type 2 or VE cadherin (vascular epithelium) also known as CD144 (Cluster of Differentiation 144), is a type of cadherin. It is encoded by the human gene CDH5. PBB Summary section title = summary text = It is a classical cadherin from… …   Wikipedia

  • T-cadherin — also known as cadherin 13, H cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. Classical cadherins are… …   Wikipedia

  • N-cadherin — See cadherins …   Dictionary of molecular biology

  • N-cadherin — noun a protein found in vertebrates such as humans, mice and chickens …   Wiktionary

  • E-cadherin — SYN: uvomorulin …   Medical dictionary

  • Cadherine — Cadherin 1; E cadherin Masse/Länge Primärstruktur 728 aa …   Deutsch Wikipedia

  • CDH2 — Cadherin 2, type 1, N cadherin (neuronal) PDB rendering based on 1ncg …   Wikipedia

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