- cadherin
- One of a class of integral-membrane glycoproteins that has a role in cell-cell adhesion and is important in morphogenesis and differentiation; E-c. is also known as uvomorulin and is concentrated in the belt desmosome in epithelial cells; N-c. is found in nerve, muscle, and lens cells helps maintain the integrity of neuronal aggregates; P-c. is expressed in placental and epidermal cells. [cell + adhere + -in]
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cad·he·rin (kad-hērґin) any of a family of over 80 calcium-dependent cell adhesion molecules, having in common the CAD domain of about 115 residues. Typically, they have 5 extracellular CAD domains (7 for protocadherins) connected to an intracellular C-terminal by a single hydrophobic sequence. Cell adhesion is by homophilic interaction.
Medical dictionary. 2011.