Melnick-Needles osteodysplasty

Melnick-Needles osteodysplasty
osteodysplasty of Melnick and Needles see under syndrome.

Medical dictionary. 2011.

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  • Melnick-Needles syndrome — a rare X linked disorder (gene locus: Xq28), caused by mutations in the gene encoding filamin A. It is characterized by severe congenital bone abnormalities manifested by distinctive facies (exophthalmos, full cheeks, micrognathia, and… …   Medical dictionary

  • osteodysplasty — SYN: Melnick Needles o.. SYN: Melnick Needles syndrome. [osteo + G. dys , bad, + plastos, formed] Melnick Needles o. a generalized skeletal dysplasia with prominent forehead and small mandible; radiographically, there are irregular ribbonlike… …   Medical dictionary

  • Needles — J.W., U.S. dentist. See N. split cast method. Carl F., U.S. pediatrician, *1935. See Melnick N. osteodysplasty, Melnick N. syndrome …   Medical dictionary

  • Melnick — John C., U.S. radiologist, *1928. See M. Needles osteodysplasty, M. Needles syndrome …   Medical dictionary

  • List of diseases (M) — A list of diseases in the English wikipedia.DiseasesTOC MaMac* Mac Ardle disease * Mac Dermot Patton Williams syndrome * Mac Dermot Winter syndromeMaci Macr* Macias Flores Garcia Cruz Rivera syndrome * Mackay Shek Carr syndrome * Macleod Fraser… …   Wikipedia

  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

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