bromocriptine

bromocriptine
A semisynthetic ergot derivative that slows dopamine turnover, inhibits prolactin secretion and release of prolactin by thyrotropin-releasing hormone, and retards tumor growth and hence is used in the treatment of hyperprolactinemia associated with various pituitary tumors; an agonist at dopamine receptors also used in Parkinson disease.

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bro·mo·crip·tine .brō-mō-'krip-.tēn n a polypeptide alkaloid C32H40BrN5O5 that is a derivative of ergot and mimics the activity of dopamine in selectively inhibiting prolactin secretion

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n.
a dopamine receptor agonist, derived from ergot, that is used in the treatment of parkinsonism. It is also used to prevent lactation and to treat disorders associated with excessive secretion of prolactin (such as prolactinoma), since it inhibits the secretion of this hormone by the pituitary gland, and to treat acromegaly, as it suppresses the release of growth hormone. The drug is administered by mouth. Fairly common side-effects are dizziness and confusion. Trade name: Parlodel.

Medical dictionary. 2011.

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  • BROMOCRIPTINE — Autre nom du mésylate de 2 bromo 見 ergocryptine, la bromocriptine est un alcaloïde semi synthétique de la série des 9 10 ergopeptides, c’est à dire des peptides de l’ergot de seigle, inscrite au tableau A. L’introduction d’un atome de brome en… …   Encyclopédie Universelle

  • Bromocriptine — ██████████90  …   Wikipédia en Français

  • Bromocriptine — Drugbox IUPAC name = Ergotaman 3 ,6 ,18 trione, 2 bromo 12 hydroxy 2 (1 methylethyl) 5 alpha (2 methylpropyl) CAS number=25614 03 3 ATC prefix=G02 ATC suffix=CB01 ATC supplemental=ATC|N04|BC01 PubChem=31101 DrugBank=APRD00622 C=32 | H=40 | Br=1 | …   Wikipedia

  • bromocriptine — noun Etymology: by shortening & alteration from bromoergocryptine, from brom + ergocryptine, an ergot derivative, from ergo + Greek kryptos hidden more at crypt Date: 1975 a polypeptide ergot derivative C32H40BrN5O5 that mimics the activity of… …   New Collegiate Dictionary

  • bromocriptine — /broh meuh krip teen/, n. Pharm. an ergot derivative, C32H40BrN5O5, that inhibits prolactin and growth hormone secretions and stimulates dopamine production in the brain, used to prevent postpartum lactation and in the treatments of acromegaly… …   Universalium

  • bromocriptine — noun An ergoline derivative and dopamine agonist used in the treatment of pituitary tumours and Parkinsons disease …   Wiktionary

  • bromocriptine — bro·mo·crip·tine …   English syllables

  • bromocriptine — n. a dopamine receptor agonist, derived from ergot, that is used in the treatment of parkinsonism. It is also used to treat disorders associated with excessive secretion of prolactin (such as prolactinoma), since it inhibits the secretion of this …   The new mediacal dictionary

  • bromocriptine — ˌbrōmōˈkripˌtēn noun ( s) Etymology: by shortening & alteration from bromoergocryptine, from International Scientific Vocabulary brom + ergocryptine, an ergot derivative, from ergo (II) + Greek kryptos hidden + International Scientific Vocabulary …   Useful english dictionary

  • bromocriptine mesylate — bro·mo·crip·tine mes·y·late (bro″mo kripґtēn) [USP] an ergot alkaloid that acts as a dopamine agonist; used to suppress prolactin secretion in the treatment of pituitary prolactinomas and of hyperprolactinemia associated amenorrhea,… …   Medical dictionary

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