Masugi nephritis

an animal model of antibody-mediated glomerulonephritis produced by injection of heterologous antibody against renal antigens. It occurs in two phases. The heterologous phase, occurring within a few hours, consists of the inflammatory response triggered by the nephrotoxic antibody binding to antigens in the glomerular basement membrane and resembles anti–GBM antibody nephritis. The autologous phase, occurring 4–6 days later, consists of the host response to the foreign antibody and does not correspond to a human disease.