contraction band necrosis

contraction band necrosis
a cardiac lesion seen in patients with neurologically induced cardiographic changes, in myocardial biopsy specimens, and in cocaine or epinephrine toxicity, characterized by hypercontracted myofibrils with contraction bands and mitochondrial damage; it is caused by calcium ion influx into dying cells, which results in the arrest of cells in the contracted state, following severe ischemia and subsequent reperfusion.

Medical dictionary. 2011.

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