suppressor mutation

suppressor mutation
a mutation that partially or completely masks phenotypic expression of another (primary) mutation but occurs at a different site from it (i.e., causes suppression); it may be intragenic or intergenic. The term is used particularly to describe a secondary mutation that restores the ability of a transfer RNA to recognize a nonsense codon that was created by the primary mutation.

Medical dictionary. 2011.

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  • suppressor mutation — suppressor mutation. См. супрессорная мутация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • suppressor mutation — noun (biology) A base change which suppresses the effect of mutations elsewhere • • • Main Entry: ↑suppress …   Useful english dictionary

  • Suppressor mutation — A suppressor mutation is a mutation that counteracts the phenotypic effects of another mutation, by intra or extragenic (intergenic) mutation.External links* [http://en.wikibooks.org/wiki/General Biology/Genetics/Mutation#Mutation The mutations… …   Wikipedia

  • suppressor mutation — Mutation that alleviates the effect of a primary mutation at a different locus. May be through almost any mechanism that can give a primary mutation, but perhaps the most interesting class are the amber and ochre supressors, where the anticodon… …   Dictionary of molecular biology

  • suppressor mutation — A mutation that reverses the effect of an earlier mutation, e.g. a mutation in a gene for a tRNA that permits it to read and override an amber mutation …   Glossary of Biotechnology

  • suppressor mutation — A mutation that overcomes the effect of another mutation and produces the normal phenotype …   Dictionary of microbiology

  • suppressor factor — (1) Factors released by T suppressor cells. (2) See suppressor mutation and ochre suppressor, opal suppressor …   Dictionary of molecular biology

  • Mutation — A permanent change, a structural alteration, in the DNA or RNA. In humans and many other organisms, mutations occur in DNA. However, in retroviruses like HIV, mutations occur in RNA which is the genetic material of retroviruses. In most cases,… …   Medical dictionary

  • suppressor — A compound that suppresses the effects of mutation or suppresses what would be a normal course of events. amber s. a mutant gene that codes for a tRNA whose anticodon has been altered so that the altered tRNA responds to UAG codons as well. * * * …   Medical dictionary

  • suppressor gene — a gene that prevents the expression of another (non allelic) gene. * * * a gene that by its presence can reverse the effects of a specific mutation in another gene; see suppression (def. 3) …   Medical dictionary

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