frameshift mutation

frameshift mutation
a mutation resulting from an insertion or deletion in a coding sequence that is not an exact multiple of 3 base pairs, so that from the point of mutation onwards, the codons are read out of phase; the reading frame of the gene is changed, and a completely different set of amino acids is made into protein.

Diagram showing the effects on translation of missense, nonsense, and frameshift mutations to a DNA segment.


Medical dictionary. 2011.

Look at other dictionaries:

  • frameshift mutation — [frām′shift΄] n. a mutation of a gene caused by the addition or deletion of any number of nucleotides other than three or multiples of three in a DNA sequence: messenger RNA derived from such DNA will carry faulty instructions for the synthesis… …   Universalium

  • frameshift mutation — [frām′shift΄] n. a mutation of a gene caused by the addition or deletion of any number of nucleotides other than three or multiples of three in a DNA sequence: messenger RNA derived from such DNA will carry faulty instructions for the synthesis… …   English World dictionary

  • frameshift mutation — frameshift mutation. См. мутация со сдвигом фазы. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Frameshift mutation — A frameshift mutation (also called a framing error) is a genetic mutation caused by indels, ie. insertion or deletion of a number of nucleotides that is not evenly divisible by three from a DNA sequence. Due to the triplet nature of gene… …   Wikipedia

  • frameshift mutation — rėmelio poslinkio mutacija statusas T sritis augalininkystė apibrėžtis Mutacija, kurios metu pakinta skaitymo rėmelis (nesintetinamas baltymas, nes, nukleotidų porai iškritus arba į jį įsiterpus, sutrinka po pažaidos visų kitų kodonų skaitymas).… …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

  • frameshift mutation — noun a genetic mutation that either inserts or deletes a series of nucleotides that is not divisible by three and thus disrupts gene expression by codons …   Wiktionary

  • frameshift mutation — A mutation that changes the reading frame of a DNA, either by the insertion or the deletion of nucleotides. Because of the triplet nature of codons, this occurs if the number of nucleotides involved is not a multiple of three …   Glossary of Biotechnology

  • complex frameshift [mutation] — complex frameshift [mutation]. См. комплексный сдвиг рамки. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • reading frameshift mutation — frameshift m …   Medical dictionary

  • Mutation — For other uses, see Mutation (disambiguation). Part of the Biology series on Evolution …   Wikipedia

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