biologic response modifier
- biologic response modifier
- (BRM), biological response modifier a method or agent, such as a cytokine, monoclonal antibody, or vaccine, that alters host-tumor interaction, usually by amplifying the antitumor mechanisms of the immune system, but also by various mechanisms directly or indirectly affecting host or tumor cell characteristics. Called also biomodulator.
Medical dictionary.
2011.
Look at other dictionaries:
modifier — That which alters or limits. biologic response m. agent that modifies host responses to neoplasms by enhancing immune systems or reconstituting impaired immune mechanisms. * * * mod·i·fi·er mäd ə .fī( ə)r n 1) one that modifies 2) a gene that… … Medical dictionary
Anakinra — drugbox IUPAC name = Recombinant human Interleukin 1 receptor antagonist protein; syn. N2 l methionyl interleukin 1 receptor antagonist (human isoform x reduced) width = 220 CAS number = 143090 92 0 ATC prefix = L04 ATC suffix = AA14 ATC… … Wikipedia
imiquimod — An immune response modifier used on the skin in the treatment of external genital and perianal warts. * * * im·i·quim·od (im″ĭ kwimґod) a biologic response modifier used topically in the treatment of condyloma acuminatum of the… … Medical dictionary
BRM — biological response modifier; biuret reactive material * * * biologic response modifier … Medical dictionary
biomodulator — bio·mod·u·la·tor (bi″o modґu la″tər) biologic response modifier … Medical dictionary
interferon alfa-2b — a synthetic form of interferon α produced by recombinant technology that acts as a biologic response modifier, used in the treatment of condylomata acuminata, hepatitis B, and chronic hepatitis C and as an antineoplastic in the treatment of… … Medical dictionary
interferon alfa-n3 — a highly purified mixture of natural human interferon proteins, manufactured from pooled human leukocytes that have been induced to produce interferon alfa n3, that acts as a biologic response modifier; used in the treatment of condylomata… … Medical dictionary
interferon beta-1a — a synthetic form of interferon β produced by recombinant DNA techniques that acts as a biologic response modifier; used in the treatment of relapsing forms of multiple sclerosis; administered intramuscularly … Medical dictionary
interferon beta-1b — a synthetic modified form of interferon β produced by recombinant DNA techniques, having 165 amino acids, substituting serine for cysteine at position 17, and lacking the carbohydrate side chains of the natural form. It has both antiviral… … Medical dictionary
interferon gamma-1b — a synthetic form of interferon γ produced by recombinant technology that acts as a biologic response modifier; used to enhance phagocytic function in order to reduce the frequency and severity of serious infections associated with chronic… … Medical dictionary