periventricular leukomalacia
- periventricular leukomalacia
- (PVL) bilateral necrosis of the white matter of the brain adjacent to the lateral ventricles, seen in the neonatal period, especially in premature newborns, and manifested by chalky, yellowish-white plaques in the white matter, with proliferation of astrocytes and microglia; cyst formation may lead to multicystic encephalopathy.
Medical dictionary.
2011.
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