- proteasome inhibitors
- a class of antineoplastic agents that disrupt the ubiquitin-proteasome system of cells, thereby interfering with growth and other cellular processes.
Medical dictionary. 2011.
proteasome inhibitors
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Proteasome inhibitor — Proteasome inhibitors are drugs that block the action of proteasomes, cellular complexes that break down proteins, like the p53 protein. Proteasome inhibitors are being studied in the treatment of cancer. In 2003, bortezomib was the first… … Wikipedia
Proteasome — Proteasomes are large protein complexes inside all eukaryotes and archaea, as well as in some bacteria. In eukaryotes, they are located in the nucleus and the cytoplasm.cite journal |author=Peters JM, Franke WW, Kleinschmidt JA |title=Distinct 19 … Wikipedia
proteasome inhibitor — A drug that blocks the action of proteasomes. A proteasome is a large protein complex that helps destroy other cellular proteins when they are no longer needed. Proteasome inhibitors are being studied in the treatment of cancer … English dictionary of cancer terms
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